Take exit #74 at Mahoning Valley. Use the ramp on the left for Lehighton to access Route 209. At the end of the ramp bear right. At the next traffic light be in the center lane to allow you to continue across the bridge. At the other end of the bridge turn right to stay on 209. Follow 209 into Jim Thorpe. Jim Thorpe is at the bottom of a steep downhill.

Take Route 93S (from the Hazleton/Conyngham area) to the end where it intersects Route 209. Turn left onto Route 209 and continue into Jim Thorpe. At the first traffic light stay straight, the road will take you directly to the historic District.

Use the Route 115 exit near the Pocono Speedway. Follow 115 towards the Speedway until you see the intersection of Route 903. Follow Route 903 all the way into Jim Thorpe. The road will turn 90 degrees to the left, and take you to a bridge. Turn left at the end of the bridge at the traffic light and follow the road into the historic district.

Parking is always interesting in Jim Thorpe. There are many places along the roads with metered parking. Race Street will be closed during the race, it is not recommended that try to park there, unless you don't mind staying until the last runner finishes. Also, not far from the start finish area, there is an all-day parking lot. The entrance is just past the train station on route 209. While there may be no parking attendant when you arrive, there may be one when you leave, and they may charge you on the way out. The lot is owned by the County of Carbon. Parking there is reasonable, it's several dollars to park there as long as you want. While the local police have been reasonable in past years, the meters are marked for use from 9-5, and can be plugged for up to two hours at a stretch.